Adderall Alternatives: Alpha Lipoic Acid

Alpha Lipoic Acid

Alpha Lipoic Acid (or simply ALA) is a naturally formed fatty acid and can be found in each and every cell of the body. We get small amounts of ALA in our diet from things like spinach, brewers yeast, rice, peas and red meat.

Because ALA is a powerful antioxidant (that is, it scavenges free radicals), researchers have been curious about its ability to help cognitive function, as it’s thought that free radical damage plays a large, critical role in declining brain function. Its success in helping to overcome various brain related issues is that unlike most of the antioxidants, ALA can easily pass through the blood-brain barrier… allowing for better absorption and a significant reduction of free radicals in the brain.

Apart from its own contribution in the various antioxidant activities, ALA also helps in the process of regeneration of other important antioxidants including Vitamin C, Vitamin E and Glutathione. This ability to recycle other free-radical neutralizers makes ALA a particularly potent antioxidant. In fact, research is ongoing related to ALA’s potential as an anti-aging powerhouse.

Because ALA is both water and fat soluble, it can fight free radicals throughout the body.

Alpha lipoic acid is a key co-factor between 2 pathways essential for cellular energy production: glycolysis and the Krebs cycle.  Playing a vital role in converting the body glucose into energy.

Most interesting are the effects of ALA related to aging and age-related neurodegenerative diseases.

Researchers are also considering it as a potential treatment for some of the major brain/cognitive problems including Alzheimer’s disease and stroke.… Read More

Adderall Alternatives: Vinpocetine

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Vinpocetine is a semisynthetic derivative alkaloid of vincamine, an extract from the periwinkle plant. Vinpocetine has been reported to have cerebral blood-flow enhancing and neuroprotective effects, and is used in the treatment of Parkinson’s disease and Alzheimer’s disease. Vinpocetine has also been gaining popularity in the field of cognitive enhancement as it may help support brain functions such as concentration and memory by activating cerebral metabolism.

A recent study aimed at determining the efficacy and safety of Vinpocetine in the improvement of cognitive function.

METHODS:

Over an 18-month period, Vinpocetine was used in the treatment of patients with mild cognitive impairment. Researchers conducted comprehensive double-blind studies using psychometrical tests (ADAS-Cog, MMSE) to assess changes patient’s cognitive performance, memory, and mental acuity.

Assessment and Analysis

Assessments were performed six times over the course of treatment, using CGIC-PGIC to evaluate the overall change in cognitive health, Age Diagnostic Laboratories (ADL) to assess the patient’s daily activity, and the Hamilton Rating Scale for Depression (HRSD) to evaluate the patient’s mood.

RESULTS:

After the 18-month treatment period, the psychometrical tests revealed massive improvement in patients with mild cognitive impairment. The investigators and patients alike reported substantial improvement including enhanced memory, performance, awareness, and mental acuity. As well as improvements in overall mood.

Reduced metabolism due to hypothyroidism has been thought to be the cause of reduced flow of blood to the brain and slowed metabolism in the brain resulting in memory-related and cognitive impairments. Clinical data shows that Vinpocetine helps to counteract this by improving blood flow to the brain – enhancing the utilization of oxygen, inhibiting platelets aggregation, improving the pliability of red blood cells and dilation of blood vessels, and boosting circulation in the brain.… Read More

Adderall Alternatives: Huperzine A

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Huperzine A Is an alkaloid derived from Huperzia Serrate. It is known to help aid memory, learning, and concentration. It works by inhibiting acetylcholinesterase, the enzyme that breaks down acetylcholine. By prolonging the life of the brain neurotransmitter acetylcholine, it enhances mental function and sharpens focus. Used worldwide for decades in the treatment of Alzheimer’s, it is considered the most potent short-term memory enhancer available.

A new study set out to test the efficacy of Huperzine A capsules on memory and learning performance of adolescent students.

METHODS:

Using double-blind and matched pair method, 34 pairs of junior middle school students were divided into two groups by normal psychological health inventory (PHI), similar memory quotient (MQ), sex, and age. The Huperzine A (HUP) group was administrated orally 2 capsules of Huperzine A (50 micrograms) b.i.d., and the placebo (PLA) group was given 2 capsules of placebo (starch and lactose) b.i.d. for 4 weeks.

Assessment and Analysis

The Wechsler Memory Scale (WMS) was used to evaluate all samples before and after the experiment. The factors evaluated by the WMS were: recognition, picture memory, reproduction, accumulation, association, tactual memory, number of recitation and understanding. Treatment Emergent Symptom Scale (TESS) was also utilized to evaluate the occurrence of side-effects from the drug. A performance assessment – in Language and Mathematics – was also incorporated to evaluate average score before and after the trial.

RESULTS:

The results showed significant cognitive improvement in students taking Huperzine A. The Memory Quotient (MQ) was significantly higher in the HUP group compared to the PLA group after the trial.… Read More

The Year of Smart Drugs

2013

It’s January.  The new year… time to focus.

That means high achievers will be looking for ways to sharpen their competitive edge and get on top.

2012 was The Year of Adderall®, with record numbers of students and young professionals using ADHD medications as cognitive enhancers to increase focus, improve concentration, and keep up with their demanding daily routines.

But growing safety and ethical issues surrounding the use of ADHD medication for non-therapeutic use has sent healthy over-achievers looking for alternatives – and they have found one in Nootropics.

Adderall Alternatives?

Nootropics, commonly known as “smart drugs,” are fueling a new category of nutritional supplement: Cognitive Energy Enhancers. Dubbed “Adderall Alternatives,” these non-prescription alternatives help healthy overachievers to improve focus, increase concentration, and enhance cognitive function.

Pioneering the science of Nootropics, industry leader PROFIDERALL has seen sales of its Cognitive Energy Enhancer grow more than 450% since 2010. This phenomenal success is a direct result of its unique Cognitive Energy Complex™, which combines nootropic ‘smart drugs’ with powerful energy compounds.

The Science of Nootropics

Nootropics improve the function of the neurotransmitter acetylcholine via muscarinic cholinergic (ACh) receptors, which are implicated in memory processes. Furthermore, they have an effect on NMDA glutamate receptors which are involved with learning and memory. Nootropics influence neuronal and vascular functions and increase cognitive function, while at the same time providing a natural source of energy to keep you alert and motivated.

Nootropics Are Changing the Way Americans Think

As growing numbers of healthy over-achievers are turning to Nootropics to work smarter… rise above the crowd… and accomplish more, 2013 is proving to be the year of “ Smart Drugs.”

Please visit www.PROFIDERALL.com to learn more about PROFIDERALL and order online.… Read More

The Year of Adderall

As 2012 comes to a close, it is safe to say this has been, for better or worse, the year of Adderall®. With a long list of headlines covering topics like Adderall Shortages, the Ethics of Smart Drugs, and Medicating Success, it seemed like there was a new article on Adderall everyday. And the popularity of the drug extended beyond the media. This year, 98% of pharmacies have experienced Adderall shortages. Given this meteoric rise of attention…

Can we all stop pretending that the rise in popularity of Adderall is directly related to anything other than students and young professionals using it as a “smart drug”???

Look, students have been using Adderall for years to improve focus and concentration. So much so that Cognitive Enhancement has become a billion dollar industry.  And it doesn’t stop when people leave college. In fact, this generation of graduates is carrying smart drugs into the workplace. It is not uncommon for young professionals to use ADHD medications to keep up with their daily routine.

It is ridiculous to think this Adderall shortage correlates with a sudden spike in cases of ADHD.  So why has all the controversy played out in the media?

The reason can be traced to the off-label use of prescription drugs. And rightfully so. Medications designed to treat ADHD are not meant for non-therapeutic use and can be addictive, potentially harmful and illegal to consume without a doctor’s permission. In addition, they are Class 2 controlled substances and rank among the most addictive substances that have a medical use.… Read More

The Ethics of Smart Drugs

The rise of awareness about the value of smart drugs has raised a question of ethics: Is the use of smart drugs cheating?

The answer is yes AND no.

The misuse of prescription drugs is, by definition, unethical; and the abuse of a controlled substance is a violation of most major corporate and academic codes of conduct – and thus technically cheating.

But…

There is absolutely nothing unethical, immoral, or unfair about trying to improve cognitive function. Is it unethical to drink a cup of coffee in the morning to wake up? Does drinking a protein shake after a gym workout give you an unfair advantage? Both are ‘tools’ to aid in physical endurance and performance. After all, taking a daily multivitamin gives you both a physical and mental advantage… and no one argues that vitamins are unethical.

So why does a double standard apply when it comes to cognitive performance?

The key to the controversy can be traced to the off-label use of prescription drugs. And rightfully so. The medications designed to treat ADHD are not meant for non-therapeutic use and can be addictive, potentially harmful and illegal to consume without a doctor’s permission. In addition, they are Class 2 controlled substances and rank among the most addictive substances that have a medical use.

What’s being missed here is a simple fact: not all smart drugs are prescription medications. Most notably Nootropics. Nootropics are safe, legal and widely available. Thus, by all prior definitions, the use of these smart drugs is neither unethical nor cheating.Read More

Back to School… Back to Work… Time to Focus.

It’s September.  Summer’s over… it’s back to school and back to work. This is the time of year when high-achievers make their move and separate from the pack by working smarter, better, faster.

And as millions of Americans return to the stress of their highly demanding schedules, once again “Smart Drugs“ are making headlines across the country.

Central to these news reports is the surprise that parents and educators express at this search for something to help students perform better. The use of “smart drugs” and the abuse of Adderall® shouldn’t come as a surprise, particularly for a generation of high achievers who know their futures lie in attending the best schools, attaining the highest grades and working for the country’s most prestigious, highest paying companies.

In fact, the only shocking thing about this story is the idea that using “smart drugs,” to study harder and improve overall academic achievement is somehow a shock to anyone. For years, college students have been using “smart drugs” to improve their study habits. And the results have been nothing short of amazing. In fact, the use of neuroenhancers have graduated into the work place, carried by a generation of young professionals that sees “smart drugs” as an important tool for success.

So what’s the problem?

To begin, prescription drugs designed to treat ADHD are not meant for non-therapeutic use and can be addictive, potentially harmful and illegal to consume without a doctor’s permission. And rightfully so. They are Class 2 controlled substances and rank among the most addictive substances that have a medical use.… Read More

PROFIDERALL’s Cognitive Energy Complex™ Triggers a Flood of Knock-Offs

PROFIDERALL® has changed the way Americans work and think. As the first (and still the only) non-prescription ‘Cognitive Energy Enhancer,’ this powerful nootropic formula is helping performance-driven young Americans increase focus, improve concentration, and boost their endurance. Now an entire generation of students and young professionals see Cognitive Energy Enhancement as an important tool for success. Calling PROFIDERALL the “Adderall Alternative,”  these healthy overachievers are using the nutritional supplement to work smarter, work longer and accomplish more.

Sales of America’s #1 Cognitive Energy Enhancer are at record highs. So it comes as no surprise that a variety of ‘copycats’ have tried to flood the market with weak knock-offs. However, none of these products, have been able to replicate PROFIDERALL’s ‘Cognitive Energy Complex’ – the unique combination of nootropic “smart drugs” and powerful energy compounds that gives the product the intense focus and incredible energy that users have come to expect.

PROFIDERALL’s Cognitive Energy Complex™ Is a Trade Secret.

With a growing interest in nootropics and the continuing controversy surrounding Adderall®, imitators are struggling to duplicate the composition and effectiveness of PROFIDERALL’s proprietary formula. But they’ve had little success.

Many knock-offs load their products with cheap stimulants, making them little more than expensive energy drinks. Others claim to include nootropics, but their formulas are filled with low dose multivitamins and do not contain the correct balance of nootropics (if they contain any nootropics at all). Some knock-offs even claim they can help you lose weight. Real nootropics are about more than just energy and have nothing to do with weight loss.… Read More

“The Great Adderall Shortage of 2011″ Leaves High Achievers Scrambling for an Alternative…

First reported in May, both The Wall Street Journal and The New York Observer chronicled a crisis among the high achiever set: a nationwide shortage of the popular prescription drug Adderall. Why would an Adderall shortage concern NYC’s movers and shakers? Well, in case you haven’t heard, the drug, which is ostensibly prescribed to combat attention deficit/hyperactivity disorder, is more commonly used by healthy young professionals and students to improve focus, concentration, and to help them keep up with their increasingly overwhelming work schedules.

To quote The Observer: ”A deadstock crisis is notable for the potential to wreck havoc on creative classes, students of all ages (during finals!), and then, of course, people actually prescribed it.”

Since these initial reports, the shortage has only gotten worse. And it’s no laughing matter for those who truly need Adderall and are under a physician’s care.

Local pharmacies, including Walgreen’s, Wal-Mart and CVS, are still feeling the effects of a shortage that began in 2010. A quick Google Trends check sees searches for “adderall shortage” increasing 10-fold in the past month. Reports are beginning to surface nationwide including California where the West Coast literati congregate and bemoan the difficulty of finding a tab of Adderall “at any cost.”

According to Adderall’s manufacturer, Shire, the Drug Enforcement Administration (DEA) restricted Adderall’s production because of its active ingredient, which is considered an amphetamine. Shire has responded to these limits by hiking the price and making fewer discounts available to consumers.

Meanwhile, the shortage is sending millions users in search of alternatives to Adderall.… Read More

The Power of Piracetam

Piracetam, often referred to as a “smart drug,” is a psychoactive substance that is widely recognised internationally for its powerful ability to improve learning and memory. It belongs to the Nootropic family of chemical substances known for the considerable improvement they bring about in cognitive reasoning, memory abilities, intelligence, and motivation. In addition to stabilizing cells in the blood and central nervous system, Piracetam also assists in alleviating oxidative and hypoxic stress. Since there are no toxic or addictive properties associated with the substace, it is commonly used to treat several neurological and physical disorders including dyslexia, senile dementia, concussions, ADHD, Alzheimer’s, and amnesia.

Tracing Its Genesis

The need for a potent learning and memory enhancing substance that has no pernicious side-effects resulted in a concerted scientific endeavor, comprising a group of Belgian scientists, under the leadership of Romanian psychologist and chemist, Dr Corneliu E. Giurgea. The sustained efforts of this group of scientists led to the synthesis of the world’s first Nootropic supplement – Piracetam. Successful trials reinforced the fact that the ‘smart drug’ is a potent tool in the fight against a host of age-related neurological conditions. Today, more than four decades after its discovery, Piracetam has emerged as the most widely tested and widely recommended Nootropic along with Oxiracetam and Aniracetam.

Thinking Better: The Benefits of Piracetam

There are numerous health benefits associated with Piracetam. Like all other Nootropics, Piracetam boosts the central nervous system. It also stimulates the corpus callosum, the switchboard between the left and right hemispheres of the brain, thus facilitating increased communication between the two sides and enabling the brain to work at its optimum efficiency.… Read More